Thermo Fisher Scientific NMDAR1 Monoclonal Antibody (54.1)
NMDAR1 단백질을 특이적으로 인식하는 mouse monoclonal antibody (clone 54.1). 다양한 종(인간, 마우스, 랫 등)에 반응하며 WB, IHC, ICC/IF 등 여러 응용에 사용 가능. 단백질 A로 정제된 액상형 항체로 연구용으로 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–5 µg/mL | 37 publications |
| Immunohistochemistry (IHC) | – | 7 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:50 | 1 publication |
| Immunohistochemistry (Frozen) (IHC (F)) | – | 1 publication |
| Immunohistochemistry - Free Floating (IHC (Free)) | – | 1 publication |
| Immunocytochemistry (ICC/IF) | 1:100 | 8 publications |
| ELISA | 0.1–1 µg/mL | 1 publication |
| Immunoprecipitation (IP) | 1–3 µg/mL | 1 publication |
| Miscellaneous PubMed (Misc) | – | 1 publication |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Published Species | Fish, Hamster, Human, Mouse, Rat, Tag |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 54.1 |
| Immunogen | Fusion protein containing sequence from the intracellular loop between transmembrane regions III and IV of NMDAR1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.1% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2533060 |
Product Specific Information
This antibody specifically recognizes the ~103 kDa NMDAR1 protein. Cross-reactivity with other NMDA receptor proteins has not been observed.
Target Information
NMDAR1 encodes a protein that is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes forming ligand-gated ion channels. These subunits contribute to synaptic plasticity, underlying memory and learning. Expression of different isoforms may be controlled by cell-specific factors, contributing to functional diversity. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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