Thermo Fisher Scientific MMP3 (Marker of Metastasis and Rheumatoid Arthritis) Recombinant Rabbit Monoclonal Antibody (MMP3/1994R)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-2 µg/mL

-

Flow Cytometry (Flow)

1-2 µg/10^6 cells

-

ELISA (ELISA)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

MMP3/1994R

Immunogen

Recombinant fragment (around aa 317-327) of human MMP3 protein if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MMP3,uniProtId:P08254-1,ncbiNodeId:9606,antigenRange:317-327,antigenLength:477,antigenImageFileName:4314-RBM3-P1ABX_MMP3_P08254-1_Rabbit.svg,antigenImageFileNamePDP:4314-RBM3-P1ABX_MMP3_P08254-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

MMP3 (stromelysin-1) belongs to the peptidase M10A subfamily. It is secreted in its pro-protein form, and is activated by extracellular proteinase cleavage. MMP3 is capable of binding to zinc and calcium ions, and has metallo-endopeptidase activity. The active enzyme degrades collagen, gelatin, fibronectin, and laminin. It is involved in normal cellular processes such as wound repair and tissue remodeling. Mutations in the gene can result in coronary heart disease 6.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.