Thermo Fisher Scientific IL24 Monoclonal Antibody (OTI3C5), TrueMAB
인간 IL24 단백질을 표적으로 하는 마우스 단클론 항체로, WB 및 IHC(P)에서 사용 가능. 고순도 친화 크로마토그래피 정제, 동결건조 형태로 제공. 연구용으로 세포 성장 억제 및 신호전달 연구에 적합.
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Applications
- Western Blot (WB): 1:2,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3C5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 52–206 of human IL24 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional round of desalting (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Interleukin 24 (IL-24), also known as melanoma differentiation-associated gene-7 (MDA-7), encodes a secreted protein homologous to the interleukin 10 (IL-10) family of cytokines.
Human IL-24 is secreted by activated peripheral blood mononuclear cells and binds to the heterodimeric receptors IL-22R1/IL-20R2 and IL-20R1/IL-20R2, activating JAK/STAT signaling pathways.
MDA-7/IL-24 selectively induces growth suppression, apoptosis, and radiosensitization in malignant gliomas in a p53-independent manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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