Thermo Fisher Scientific IL24 Monoclonal Antibody (OTI4D1), TrueMAB
인간 IL24 단백질(aa 52-206)에 특이적인 Mouse IgG1 단클론 항체로, Western blot에 최적화됨. 무보존제, 동결건조 형태로 제공되며 재구성 후 1 mg/mL 농도 유지. 연구용으로 JAK/STAT 신호 및 세포사멸 관련 연구에 활용 가능.
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Thermo Fisher Scientific IL24 Monoclonal Antibody (OTI4D1), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4D1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 52–206 of human IL24 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Interleukin 24 (IL-24), also known as melanoma differentiation-associated gene-7 (mda-7), encodes a secreted protein with significant homology to the interleukin 10 (IL-10) cytokine family.
Human IL-24 is secreted by activated peripheral blood mononuclear cells and binds the heterodimeric receptors IL-22R1/IL-20R2 and IL-20R1/IL-20R2, leading to activation of JAK/STAT signaling pathways.
Mda-7/IL-24 selectively induces growth suppression, apoptosis, and radiosensitization in malignant gliomas independent of p53.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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