Thermo Fisher Scientific TGR5 Polyclonal Antibody
TGR5/GPBAR1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF에 사용 가능. Human, Mouse, Rat 반응성. Affinity chromatography로 정제된 액상형 항체로 연구용에 적합.
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Thermo Fisher Scientific TGR5 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 | - |
| Immunocytochemistry (ICC/IF) | 2 µg/mL | - |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from C-terminus of the human TGR5/GPBAR1 protein (UniProt Q8TDU6) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2540708 |
Target Information
This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. It functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces intracellular cAMP production, activation of MAP kinase signaling, and receptor internalization. The receptor is involved in suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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