Thermo Fisher Scientific TGR5 Polyclonal Antibody
Rabbit polyclonal antibody recognizing TGR5 (BG37) protein. Validated for Western blot applications. Suitable for research on GPCR-mediated bile acid signaling. Supplied as liquid, unconjugated form, stored at -20°C. For research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:5,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide (41 WDRRLRSPPA 50) of BG37/TGR5 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2540709 |
Target Information
This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. It functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces intracellular cAMP production, activation of a MAP kinase signaling pathway, and receptor internalization. The receptor is implicated in suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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