Thermo Fisher Scientific DOCK8 Monoclonal Antibody (OTI5C4), TrueMAB
DOCK8 단백질을 특이적으로 인식하는 마우스 단클론 항체로, Western blot 및 면역세포염색에 적합합니다. 인간 시료에 반응하며, 동결건조 형태로 제공됩니다. 고순도 친화 크로마토그래피 정제 및 안정한 PBS 완충액에 보존됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5C4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 833–1160 of human DOCK8 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The Dedicator of cytokinesis protein 8 (DOCK8) is a member of the DOCK180 family of guanine nucleotide exchange factors.
DOCK8 plays an essential role in humoral immune responses and is critical for proper B cell immunological synapse formation.
Mutations in this gene are associated with the autosomal recessive form of hyper-IgE syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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