Thermo Fisher Scientific SEMA7A Monoclonal Antibody (MEM-150), FITC
인간 CD108(SEMA7A) 항원을 인식하는 Mouse IgM 형 단일클론 항체로, FITC 형광 표지되어 Flow Cytometry에 적합합니다. 액상 형태로 제공되며, 4°C 암소 보관이 필요합니다. 세포 표면 단백질 분석 및 면역학 연구용으로 사용됩니다.
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Applications
- Flow Cytometry (Flow)
Tested Dilution
- 20 µL per 100 µL whole blood or 10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgM |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MEM-150 |
| Immunogen | T cell line HPB-ALL |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | TBS, pH 8.0, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2186148 |
Additional Formats
Product Specific Information
This antibody reacts with CD108 (JMH blood group antigen), an 80 kDa GPI-anchored extracellular glycoprotein expressed on various cell types including erythrocytes and lymphoblasts. At low levels, it is present on circulating lymphocytes.
Target Information
CD108 (Sema7A) is a GPI-anchored semaphorin family member that enhances central and peripheral axonal growth and is required for proper axon tract formation during embryogenesis. It also regulates osteoclast differentiation and pre-osteoblastic cell migration, and in the immune system, affects cell proliferation, chemotaxis, and cytokine release. On erythrocytes, CD108 defines the JMH (John-Milton-Hagen) human blood group. CD108 signals through its receptors plexin C1 and β1 integrins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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