
Thermo Fisher Scientific CD31 Monoclonal Antibody (MEM-05), FITC
CD31(PECAM-1)을 인식하는 FITC 결합 단일클론 항체로, 인간 시료에 반응합니다. Flow cytometry 및 ICC/IF에 사용 가능하며, 액상 형태로 제공됩니다. 4°C 암소 보관하며, 형광 특성은 498/517 nm입니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested dilution: Not specified
- View 1 publication
Flow Cytometry (Flow)
- Recommended use: 20 µg/100 µL whole blood or 10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MEM-05 |
| Immunogen | Leucocytes from a patient suffering from a LGL type leukaemia |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1072127 |
Available Formats
- Unconjugated
- Alexa Fluor 488
- APC
- Biotin
- PE
- Custom conjugation available upon request
Product Specific Information
This antibody reacts with an extracellular epitope of CD31 (PECAM-1), a 130–140 kDa type I transmembrane glycoprotein expressed on monocytes, platelets, granulocytes, endothelial cells, and stem cells of the myeloid lineage.
Target Information
CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling via dual ITIM motifs. It is expressed ubiquitously within the vascular compartment, mainly at junctions between adjacent cells. The N-terminal Ig-like domain mediates homophilic binding, crucial for cell-cell interactions.
CD31 plays diverse roles in:
- Integrin-mediated cell adhesion
- Transendothelial migration
- Angiogenesis
- Apoptosis
- Regulation of immunoreceptor signaling
- Autoimmunity and thrombosis
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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