Thermo Fisher Scientific CD56 Monoclonal Antibody (ERIC-1)
인간 CD56(NCAM)에 특이적인 Mouse IgG1 단일클론 항체로 다양한 면역분석(WB, IHC, Flow 등)에 사용 가능. Protein A로 정제된 액상 형태이며, 고감도 신경세포 및 NK세포 표지에 적합. -20°C 보관, 연구용 전용.
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Thermo Fisher Scientific CD56 Monoclonal Antibody (ERIC-1)
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:100–1:2,000 | - |
| Immunohistochemistry (IHC) | - | View 3 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:500 | - |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:10–1:500 | - |
| Immunocytochemistry (ICC/IF) | 1:10–1:500 | View 2 publications |
| Flow Cytometry (Flow) | 1:10–1:1,000 | - |
| ELISA | 1:100–1:2,000 | - |
| Immunoprecipitation (IP) | 1:10–1:500 | - |
| Radioimmune Assays (RIA) | 1:100–1:2,000 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ERIC-1 |
| Immunogen | CD56 positive cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1017970 |
Product Specific Information
Suggested positive control: antigen standard for NCAM1 (transient overexpression lysate).
Target Information
CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of the immunoglobulin family that serves as an adhesive molecule and is ubiquitously expressed in the nervous system in isoforms ranging from 120–180 kDa.
CD56 is found on T cells and NK cells, and is involved in cell migration, axonal growth, pathfinding, and synaptic plasticity. Polysialic modification reduces CD56-mediated cell adhesion.
Through its extracellular region, CD56 mediates homophilic and heterophilic interactions by binding extracellular matrix components such as laminin and integrins.
CD56 is expressed on most neuroectodermal-derived cell lines, tissues, and neoplasms such as retinoblastoma, medulloblastoma, astrocytomas, and neuroblastoma.
Further, CD56 is a widely used neuroendocrine marker with high sensitivity for neuroendocrine tumors and ovarian granulosa cell tumors.
Diseases associated with CD56 dysfunction include rabies and blastic plasmacytoid dendritic cell neoplasms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: MA1-46055_CD56_NCAM_P13591-2_House_mouse.svg, MA1-46055_CD56_NCAM_P13591-2_House_mouse_PDP.jpeg)
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