Thermo Fisher Scientific Phospho-CXC Chemokine Receptor 5 (Thr367, Ser368) Polyclonal Antibody
인간 CXCR5의 Thr367/Ser368 인산화 부위를 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공됩니다. 단기 4°C, 장기 -20°C 보관을 권장합니다.
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Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human CXCR5 around the phosphorylation site of Thr367/Ser368 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
CXCR5 (C-X-Chemokine Receptor Type 5, CD185), also known as Burkitt lymphoma receptor 1 (BLR1), belongs to the CXC chemokine receptor family.
It is a G protein-coupled seven transmembrane receptor for chemokine BLC and is specifically expressed in Burkitt’s lymphoma and lymphatic tissues such as lymph node follicles and spleen.
CXCR5 plays an essential role in B cell migration and is expressed in various human and animal tissues including blood, salivary gland, lymphatic organs, bone marrow, brain, liver, skin, spleen, stomach, and tonsil.
G-protein Coupled Receptors (GPCRs) share a structural motif of seven membrane-spanning helices and exist in active and inactive forms.
They are key signaling molecules involved in numerous physiological processes and are major targets in pharmacological research.
Notable GPCR-targeted drugs include Zyprexa (Eli Lilly) and Claritin (Schering-Plough), used for mental health and allergy treatments respectively.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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