Thermo Fisher Scientific Phospho-CXC Chemokine Receptor 5 (Thr370, Thr371) Polyclonal Antibody
CXCR5 단백질의 Thr370/Thr371 인산화 부위를 인식하는 토끼 폴리클로날 항체입니다. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 인체 시료 반응성이 있으며, 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human CXCR5 around the phosphorylation site of Thr370/Thr371. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
CXCR5 (C-X-Chemokine Receptor Type 5, CD185), also known as Burkitt lymphoma receptor 1 (BLR1), belongs to the CXC chemokine receptor family.
It is a G protein-coupled seven-transmembrane receptor for chemokine BLC and is specifically expressed in Burkitt’s lymphoma and lymphatic tissues such as lymph node follicles and spleen.
CXCR5 plays an essential role in B cell migration and is expressed in human blood and salivary gland, as well as in various animal tissues including lymphatic organs, bone marrow, brain, liver, skin, spleen, stomach, and tonsil.
G-protein Coupled Receptors (GPCRs) form one of the largest families of signaling molecules, all sharing a seven-membrane-spanning helical structure.
They exist in active and inactive forms, mediating cellular signaling via G-proteins and downstream effectors.
The regulation of GPCRs has significant implications for cell physiology and pharmacological research, with several GPCR-targeted drugs already in clinical use.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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