Thermo Fisher Scientific Phospho-RPS6KB2 (Ser423) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunocytochemistry (ICC/IF)

1:100-1:500

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human RPS6KB2(Accession Q9UBS0), corresponding to amino acid residues around phosphorylated Ser423. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RPS6KB2,uniProtId:Q9UBS0-1,ncbiNodeId:9606,antigenRange:423,antigenLength:482,antigenImageFileName:PA5-105036_RPS6KB2_Q9UBS0-1_Rabbit.svg,antigenImageFileNamePDP:PA5-105036_RPS6KB2_Q9UBS0-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

sequential chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2816509

Product Specific Information

Antibody detects endogenous levels of p70 S6 Kinase beta only when phosphorylated at Serine 423.

Target Information

RPS6KB2 (p70S6K beta) is a serine/threonine kinase with 2 non-identical kinase catalytic domains which phosphorylates the S6 ribosomal protein and eukaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.