Thermo Fisher Scientific Human CCL2 (MCP-1) Recombinant Protein

Applications and Tested Dilution

Product Specifications

Product Specific Information

Carrier-Free

Reconstitution:
Centrifuge the vial briefly before opening to bring contents to the bottom. Reconstitute the lyophilized protein in sterile, distilled water to 0.1–0.5 mg/mL. Apportion the reconstituted protein into working aliquots and store at ≤ -20°C. Make further dilutions in medium or buffered solution containing carrier protein (e.g., PBS with 0.1% BSA).

Storage:
Store the lyophilized protein at 2–8°C, preferably desiccated. Upon reconstitution, apportion into working aliquots and store at ≤ -20°C (not in a frost-free freezer). Avoid repeated freeze–thaw cycles.

Target Information

This gene is part of a cytokine gene cluster on chromosome 17q. Cytokines are secreted proteins involved in immunoregulatory and inflammatory processes. The encoded protein belongs to the CXC subfamily, characterized by two cysteines separated by a single amino acid. This cytokine shows chemotactic activity for monocytes and basophils, but not for neutrophils or eosinophils. It is implicated in diseases with monocytic infiltrates, such as psoriasis, rheumatoid arthritis, and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.