Thermo Fisher Scientific CD42b Monoclonal Antibody (AK2), PE
CD42b 단백질을 인식하는 마우스 단클론 항체로 PE 형광체가 결합된 제품입니다. 사람 시료에서 반응하며 유세포분석(Flow Cytometry)에 적합합니다. 혈소판 활성화 및 응집 관련 연구에 활용됩니다. 단백질 A로 정제되었으며 4°C 암소 보관 권장.
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Thermo Fisher Scientific CD42b Monoclonal Antibody (AK2), PE
Applications
- Flow Cytometry (Flow)
Tested Dilution: Neat
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | AK2 |
| Immunogen | Human platelet glycoproteins |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Lyophilized |
| Concentration | Not Determined |
| Purification | Protein A |
| Storage Buffer | PBS with 1% BSA, 5% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2538070 |
Additional Formats
Product Specific Information
- Reconstitute with 1 mL of distilled water.
- After reconstitution, store undiluted at 4ºC in the dark.
- For FACS analysis, use 10 µL of the suggested working dilution to label 1×10⁶ cells in 100 µL.
Target Information
CD42b is a platelet activation marker involved in coagulation and aggregation. It interacts with extracellular matrix and adhesion molecules and is regulated by VEGF and PDGF.
CD42b forms part of the GPIb-IX-V receptor complex, essential for platelet-rich thrombus formation by binding to von Willebrand factor (VWF) and other coagulation factors.
It is expressed on platelets and megakaryocytes in bone marrow. Mutations in CD42b are associated with Bernard-Soulier syndrome and platelet-type von Willebrand disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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