Thermo Fisher Scientific ABCB6 Polyclonal Antibody
Human ABCB6 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western Blot, IHC, ICC 등 다양한 응용에 사용 가능. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 리오필라이즈 형태로 -20°C에서 안정적 보관 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.1–0.5 µg/mL | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 0.5–1 µg/mL | - |
| Immunocytochemistry (ICC/IF) | 0.5–1 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to human ABCB6 (818–842aa: YADMWQLQQGQEETSEDTKPQTMER) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5 mg BSA |
| Contains | 0.05 mg sodium azide, 0.05 mg thimerosal |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745809 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
The membrane-associated protein encoded by the ABCB6 gene is a member of the ATP-binding cassette (ABC) transporter superfamily. These proteins transport various molecules across cellular membranes and are divided into seven subfamilies. ABCB6 belongs to the MDR/TAP subfamily, which is involved in multidrug resistance and antigen presentation. This half-transporter likely contributes to mitochondrial function. The gene, localized to chromosome 2q26, is considered a candidate for lethal neonatal metabolic syndrome, a mitochondrial disorder.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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