Thermo Fisher Scientific ABCB4 Polyclonal Antibody
ABCB4 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, Flow cytometry 등 다양한 응용에 사용 가능. E.coli 유래 ABCB4 항원으로 제조되었으며, 고순도 항원 친화 크로마토그래피 정제. 연구용으로만 사용.
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Thermo Fisher Scientific ABCB4 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–5 µg/mL |
| Flow Cytometry (Flow) | 1–3 µg/1×10⁶ cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E.coli-derived human ABCB4 recombinant protein (Position: A601–A720) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 4 mg trehalose |
| Contains | No preservative |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745808 |
Product Specific Information
Human Apolipoprotein A I shares 64% and 61.7% amino acid sequence identity with mouse and rat Apolipoprotein A I, respectively.
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
The membrane-associated protein encoded by ABCB4 is a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes.
ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).
This protein belongs to the MDR/TAP subfamily, which is involved in multidrug resistance and antigen presentation.
ABCB4 encodes a full transporter and member of the p-glycoprotein family of membrane proteins, with phosphatidylcholine as its substrate.
It may function in the transport of phospholipids from liver hepatocytes into bile.
Alternative splicing results in several products of undetermined function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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