Thermo Fisher Scientific MEK3/MEK6 Recombinant Rabbit Monoclonal Antibody (JJ087-09)
MEK3/MEK6 단백질을 인식하는 재조합 토끼 단일클론 항체로, 높은 특이성과 민감도를 제공. Western blot, IHC, ICC/IF, Flow cytometry 등 다양한 응용 가능. HEK293 세포 발현 시스템 기반으로 생산되어 로트 간 일관성 보장. 연구용으로만 사용.
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Thermo Fisher Scientific MEK3/MEK6 Recombinant Rabbit Monoclonal Antibody (JJ087-09)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JJ087-09 |
| Immunogen | Synthetic peptide within Human MEK3+MEK6 aa 298–347 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809731 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal production candidates.
Advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to the rabbit immune repertoire
Target Information
The MEK3/MEK6 gene encodes a dual specificity protein kinase functioning as a mitogen-activated protein kinase kinase. These kinases phosphorylate and activate p38 MAP kinase in response to inflammatory cytokines or environmental stress.
As a key component of the p38 MAPK signaling pathway, this gene is involved in:
- Stress-induced cell cycle arrest
- Transcription activation
- Apoptosis
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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