Thermo Fisher Scientific CBX7 Recombinant Rabbit Monoclonal Antibody (JM44-63)
Thermo Fisher Scientific의 CBX7 Recombinant Rabbit Monoclonal Antibody (JM44-63)는 인간 CBX7 단백질을 표적으로 하는 고특이성 항체입니다. Western blot 및 Flow cytometry에 최적화되어 있으며, 재조합 기술로 생산되어 로트 간 일관성과 높은 감도를 제공합니다.
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- MA532767
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- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Flow Cytometry (Flow)
- Tested Dilution: 1:50–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JM44-63 |
| Immunogen | Recombinant protein within Human CBX7 (aa 1–190) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2810044 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems are developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
Target Information
The protein encoded by this gene is one subunit of a trimeric complex forming a highly conserved transcription factor that binds to CCAAT motifs in promoter regions of various genes.
Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds DNA with high specificity and affinity.
The A subunit mediates sequence-specific interactions, functioning as a regulatory subunit.
Post-transcriptional regulation may occur via protein degradation or translational control, and alternative splicing in the glutamine-rich activation domain shows tissue-specific preferences for isoforms.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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