
Thermo Fisher Scientific Cyclophilin F Recombinant Rabbit Monoclonal Antibody (JM71-39)
Cyclophilin F 단백질을 인식하는 재조합 토끼 단클론 항체로, WB와 IHC(P)에서 검증됨. 높은 특이성과 민감도를 제공하며, 로트 간 일관성이 우수함. 단백질 접힘 및 세포사멸 연구에 적합. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JM71-39 |
| Immunogen | Synthetic peptide within Human Cyclophilin F (aa 30–79) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2810046 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The specific antibody DNA sequences are cloned from immunoreactive rabbits, and individual clones are screened to select the best candidates for production.
Advantages include:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broad immunoreactivity due to large rabbit immune repertoire
Target Information
Cyclophilin F는 peptidyl-prolyl cis-trans isomerase (PPIase) 계열 단백질로, 단백질 내 프롤린 잔기의 cis-trans 이성질화 반응을 촉매하여 단백질 접힘을 촉진합니다.
이 단백질은 미토콘드리아 내막의 투과성 전이공(permeability transition pore)의 구성 요소이며, 해당 공의 활성화는 세포자멸사(apoptosis) 및 괴사(necrosis) 유도에 관여하는 것으로 알려져 있습니다.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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