Thermo Fisher Scientific CD4 Monoclonal Antibody (MEM-241), FITC
인간 CD4 항원을 인식하는 마우스 단클론 항체로, FITC 형광 표지되어 Flow Cytometry에 적합합니다. 4°C 암소 보관, 동결 금지. PBS(pH 7.4) 및 0.2% BSA 함유, 15mM sodium azide 포함. 연구용으로만 사용 가능합니다.
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Applications
- Flow Cytometry (Flow): 20 µL/1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MEM-241 |
| Immunogen | 2 N-terminal domains of human CD4 fused to human IgG1 Fc |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1072282 |
Additional Formats
- Unconjugated (Cat. MA1-19305)
- APC (Cat. MA1-19470)
- Biotin (Cat. MA1-19521)
- PE (Cat. MA1-19653)
- PerCP (Cat. MA1-19775)
- Custom conjugation available upon request
Product Specific Information
This antibody recognizes an extracellular epitope of the CD4 antigen, a 55 kDa transmembrane glycoprotein expressed on a subset of T lymphocytes (“helper” T-cells) and also on monocytes, tissue macrophages, and granulocytes.
Target Information
The CD4 antigen is involved in the recognition of MHC class II molecules and serves as a co-receptor for HIV. It is primarily expressed on T helper cells but can also be found on monocytes, macrophages, and dendritic cells. CD4 expression is observed in thymus, lymph nodes, tonsils, spleen, and certain non-lymphoid tissues such as brain and gut. CD4 plays a key role in initiating or enhancing T-cell activation via association with the T-cell receptor complex and protein tyrosine kinase Lck. It may also mediate neuronal damage in infectious and immune-mediated CNS diseases. Multiple alternatively spliced transcripts have been identified (RefSeq, July 2017).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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