Thermo Fisher Scientific HLA-G Monoclonal Antibody (MEM-G/11), FITC
HLA-G 단백질을 인식하는 FITC 표지 단일클론 항체로, 유세포분석(Flow Cytometry)에 적합합니다. 인간 시료 반응성이 있으며, 4°C 암소 보관이 필요합니다. MEM-G/11 클론 기반으로 고순도 정제되어 연구용으로 사용됩니다.
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Applications
- Flow Cytometry (Flow): 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MEM-G/11 |
| Immunogen | Recombinant human HLA-G refolded with beta-2 Microglobulin and peptide |
| Conjugate | FITC (Fluorescein) |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1076723 |
Additional Formats
- Unconjugated (MA1-19350)
- Request custom conjugation (Custom Form)
Product Specific Information
This antibody recognizes an extracellular epitope of the HLA-G1 antigen.
HLA-G belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and is expressed on the surface of trophoblast cells.
Target Information
HLA-G belongs to the HLA class I heavy chain paralogues. This molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin).
The heavy chain (~45 kDa) is membrane-anchored and encoded by 8 exons:
- Exon 1: leader peptide
- Exons 2–3: α1, α2 domains (peptide binding)
- Exon 4: α3 domain
- Exon 5: transmembrane region
- Exon 6: cytoplasmic tail
HLA-G is expressed on fetal-derived placental cells.
HLA and MHC antibodies are important in Immunopeptidomics, aiding in the identification and characterization of neoantigens through HPLC-tandem mass spectrometry.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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