Thermo Fisher Scientific Phospho-COX4 (Ser58) Polyclonal Antibody
Phospho-COX4 (Ser58) 항체로 인간, 마우스, 랫트 시료에서 인산화된 COX IV 검출에 적합. Western blot, IHC, ICC/IF에 사용 가능. 고순도 정제 및 PBS/글리세롤 보존. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human COX IV around the phosphorylation site of Ser58 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899199 |
Product Specific Information
Antibody detects endogenous levels of COX IV only when phosphorylated at Ser58.
Target Information
Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that transfers electrons from cytochrome c to molecular oxygen, contributing to the proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. COX4 (COX4I1) is one of the nuclear-encoded subunits and may play a role in regulation and assembly of the complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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