Thermo Fisher Scientific ALK Monoclonal Antibody (OTI3E7), TrueMAB
인간 ALK 단백질을 인식하는 Rat IgG1 단클론 항체로, Western blot 및 Luminex 분석에 적합합니다. 고순도 친화 크로마토그래피 정제, PBS/BSA/glycerol 완충액에 보존되며 -20°C에서 안정적으로 보관됩니다. 연구용으로만 사용됩니다.
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Applications
- Western Blot (WB): 1:2,000
- Luminex (LUM): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rat / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3E7 |
| Immunogen | Full-length human recombinant protein of human ALK produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Anaplastic Lymphoma Receptor Tyrosine Kinase (ALK) belongs to the insulin receptor superfamily and is vital for brain development. Mutations, rearrangements, and amplifications in the ALK gene are associated with tumors such as anaplastic large cell lymphoma, neuroblastoma, and non-small cell lung cancer.
Chromosomal rearrangements often create fusion genes, notably NPM-ALK, which produce oncogenic proteins. ALK encodes a receptor tyrosine kinase with transmembrane and extracellular domains, and shares high sequence similarity with LTK.
ALK plays an essential role in neuronal development and function within the nervous system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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