Thermo Fisher Scientific CD80 Polyclonal Antibody
Human CD80 단백질을 인식하는 Goat Polyclonal Antibody로 Western Blot에 최적화됨. 비접합(Unconjugated) 형태이며 0.5 mg/mL 농도의 액상 제품. TBS 기반 버퍼에 0.5% BSA 및 sodium azide 함유. -20°C에서 보관, 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 0.5–3 µg/mL
- Publications: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (HLRVNQTFNWNTTK) corresponding to the internal amino acids of CD80 (aa 222–236) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_11005044 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 4,000.
Target Information
CD80 (B7-1) and CD86 (B7-2) are ligands of the T cell costimulatory molecule CD28 and the inhibitory receptor CTLA-4 (CD152). Both B7 molecules are expressed on antigen-presenting cells and are essential for T cell activation.
CD80 is rapidly induced on the surface of activated B cells, EBV-transformed B cell lines, Burkitt’s lymphoma cell lines, follicular B lymphoma cells, T cells, and monocytes.
The B-lymphocyte activation antigen B7-1 provides regulatory signals for T lymphocytes through binding to CD28 and CTLA4.
Diseases associated with CD80 dysfunction include gallbladder squamous cell carcinoma and myocarditis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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