Thermo Fisher Scientific DTX3 Polyclonal Antibody
DTX3 단백질을 표적으로 하는 Thermo Fisher Scientific의 염소 유래 다클론 항체. Western blot 및 IHC에 사용 가능하며 인간과 마우스 반응성. 0.5 mg/mL 농도, TBS 버퍼에 보관, 연구용 전용.
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Applications
Western Blot (WB)
- Tested Dilution: 0.2–0.5 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (KNKVTVSKPVWD) corresponding to internal amino acids of DTX3 (aa 16–27) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10977847 |
Product Specific Information
This antibody is predicted to react with bovine, human, and rat based on sequence homology.
Tested in Peptide ELISA: antibody detection limit dilution 8,000.
Target Information
Regulator of Notch signaling, a pathway involved in cell-cell communication that governs diverse cell-fate determinations.
DTX3 likely acts as both a positive and negative regulator of Notch depending on developmental and cellular context.
Functions as a ubiquitin ligase protein in vitro, suggesting regulation of the Notch pathway via ubiquitin ligase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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