Thermo Fisher Scientific NRGN Polyclonal Antibody
NRGN 단백질을 인식하는 Thermo Fisher Scientific의 산양 유래 폴리클로날 항체입니다. Western blot 및 IHC(P) 분석에 적합하며, 인간과 서열 상 유사한 소 및 개에서도 반응이 예측됩니다. 액상 형태로 제공되며 안정적인 저장 용액을 포함합니다.
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Thermo Fisher Scientific NRGN Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 0.1–0.3 µg/mL
- Immunohistochemistry (Paraffin) (IHC (P)): 4–6 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (KIKSGERGRKG) corresponding to internal amino acids of NRGN (aa 45–56) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_10987468 |
Product Specific Information
- Predicted to react with bovine and canine based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 8,000.
Target Information
Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. It encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene includes four exons and three introns; exons 1 and 2 encode the protein, while exons 3 and 4 contain untranslated sequences.
NRGN is suggested to be a direct target for thyroid hormone in the human brain, and regulation of its expression may contribute to the neurological effects of hypothyroidism during development and adulthood.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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