Thermo Fisher Scientific BACH1 Recombinant Rabbit Monoclonal Antibody (8A8X1)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:2,000-1:8,000

-

ELISA (ELISA)

1 µg/mL

-

ChIP assay (ChIP)

5 µg antibody for 10 µg-15 µg of Chromatin

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

8A8X1

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 410-736 of human BACH1 (NP_001177.1). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:BACH1,uniProtId:O14867-1,ncbiNodeId:9606,antigenRange:410-736,antigenLength:736,antigenImageFileName:MA5-51374_BACH1_O14867-1_Rabbit.svg,antigenImageFileNamePDP:MA5-51374_BACH1_O14867-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.07 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_3093683

Product Specific Information

Immunogen sequence: TPCQMQLSPA VAKDGSEQIS QKRSECPWLG IRISESPEPG QRTFTTLSSV NCPFISTLST EGCSSNLEIG NDDYVSEPQQ EPCPYACVIS LGDDSETDTE GDSESCSARE QECEVKLPFN AQRIISLSRN DFQSLLKMHK LTPEQLDCIH DIRRRSKNRI AAQRCRKRKL DCIQNLESEI EKLQSEKESL LKERDHILST LGETKQNLTG LCQKVCKEAA LSQEQIQILA KYSAADCPLS FLISEKDKST PDGELALPSI FSLSDRPPAV LPPCARGNSE PGYARGQESQ QMSTATSEQA GPAEQCRQSG GISDFCQQMT DKCTTDE

Target Information

BACH1.3 is a transcription factor that belongs to the capncollar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo and/or hetero oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene. Some exons of this gene overlap with some exons from the C21orf41 gene, which is transcribed in an opposite orientation to this gene, but which does not seem to encode a protein.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.