Thermo Fisher Scientific DRD2 Recombinant Rabbit Monoclonal Antibody (HL1478)
DRD2 단백질을 표적으로 하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체(HL1478). Western blot, IHC, ICC/IF 등 다양한 응용에 적합. 인간, 마우스, 랫트 반응성. Protein A로 정제된 액상 형태, 1 mg/mL 농도. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | HL1478 |
| Immunogen | Recombinant protein encompassing a sequence within the N-terminal region of Human Dopamine Receptor D2 (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2938132 |
Product Specific Information
- Store as concentrated solution.
- Centrifuge briefly prior to opening vial.
Target Information
The DRD2 Dopamine Receptor is involved in the neuromodulation of appetitive behaviors. DRD2 may be linked to alcoholism and other substance-use disorders. Mutations in DRD2 in mice lead to suppression of reward behavior with morphine and reduction of spontaneous movements, resembling Parkinson’s disease.
Three alternatively spliced isoforms have been identified. DRD2 is expressed in various regions of the brain, aorta, artery, eye, and spinal cord. ESTs have been isolated from normal pituitary and in brain, colon, lung, pancreas, and skeletal muscle cancer libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지: MA5-47060_DRD2_P14416-1_Rabbit.svg, MA5-47060_DRD2_P14416-1_Rabbit_PDP.jpeg)
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