Thermo Fisher Scientific Pyranose Oxidase Polyclonal Antibody

Applications

Product Specifications

Product Specific Information

Store vial at 4°C prior to restoration. For extended storage, aliquot contents and freeze at -20°C or below. Avoid freeze/thaw cycles. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use.

Anti-Pyranose Oxidase is an IgG fraction antibody purified from monospecific antiserum by a multi-step process including delipidation, salt fractionation, and ion exchange chromatography followed by extensive dialysis. Immunoelectrophoresis assay resulted in a single precipitin arc against anti-Goat Serum as well as purified and partially purified Pyranose Oxidase (E.coli). Cross-reactivity against Pyranose Oxidase from other sources is unknown.

Target Information

Pyranose Oxidase catalyzes the oxidation of various aldopyranoses and disaccharides at carbon-2 to form 2-keto sugars, with concurrent reduction of O₂ to H₂O₂. It contributes to lignin degradation in wood rot fungi by producing H₂O₂, an essential cosubstrate for ligninolytic peroxidases such as lignin peroxidase and manganese-dependent peroxidase. The preferred substrate is D-glucose, converted to 2-dehydro-D-glucose. It also acts on D-xylose, L-sorbose, D-galactose, and 1,5-anhydroglucitol, a diagnostic marker of diabetes mellitus.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.