Thermo Fisher Scientific SCARB1 Monoclonal Antibody (OTI1F3), TrueMAB

Applications and Tested Dilutions

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

High-density lipoproteins (HDLs) play a critical role in cholesterol metabolism, and their plasma concentrations are inversely correlated with the risk of atherosclerosis.
SR-BI binds HDLs and mediates selective uptake of HDL cholesteryl ester. It is expressed primarily in the liver and nonplacental steroidogenic tissues and facilitates selective cholesterol uptake through a distinct mechanism.
In mice, SR-BI plays a key role in determining plasma lipoprotein cholesterol levels and cholesterol accumulation in the adrenal gland.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.