
Thermo Fisher Scientific FLIP Polyclonal Antibody
FLIP 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot 및 Immunocytochemistry에 적합. 인간 및 생쥐 반응성. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 신뢰성 제공. 연구용으로만 사용 가능.
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Thermo Fisher Scientific FLIP Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 2 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide corresponding to amino acids 180–230 at C-terminus of human FLIP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | 2–8°C for up to 3 months; for long-term storage, store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153899 |
Product Specific Information
In Western blot applications, this antibody detects bands at approximately 25 kDa and 35 kDa.
A suggested positive control is Jurkat cell lysate.
PA5-19899 can be used with blocking peptide PEP-0025.
Target Information
FLIP (CFLAR) is an apoptosis regulator protein that serves as a key link between cell survival and death pathways in mammalian cells.
It acts as an inhibitor of TNFRSF6-mediated apoptosis. A proteolytic fragment (p43) may remain in the death-inducing signaling complex (DISC), blocking further recruitment and processing of caspase-8.
Full-length and shorter isoforms can either induce or inhibit TNFRSF-triggered apoptosis.
FLIP lacks enzymatic (caspase) activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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