Thermo Fisher Scientific CDH5 Monoclonal Antibody (OTI1E1), TrueMAB
인간 CDH5(VE-cadherin, CD144)에 특이적인 단클론 항체로 Western blot에 최적화됨. 항원은 인간 CDH5 아미노산 48-333 구간을 기반으로 제작. 동결건조 형태로 제공되며, PBS 버퍼에 trehalose 포함. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 48–333 of human CDH5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
VE-cadherin (CD144) is a calcium-dependent cell-cell adhesion glycoprotein belonging to the cadherin superfamily. It is located on chromosome 16 within a six-cadherin cluster and plays a role in endothelial cell cohesion and junction organization. VE-cadherin consists of five extracellular cadherin repeats, a transmembrane region, and a conserved cytoplasmic tail. It may be involved in loss of heterozygosity events in breast and prostate cancer. An alternative splice variant has been described, though the full-length sequence has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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