Thermo Fisher Scientific CRP Polyclonal Antibody
CRP 단백질을 인식하는 염소 유래 폴리클로날 항체로, Western blot, IHC, ELISA, IP 등 다양한 면역분석에 적합합니다. 동결건조 형태로 제공되며, 장기 보관 시 -20°C 이하에서 안정적으로 유지됩니다. 연구용으로만 사용 가능합니다.
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2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CRP Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (IHC) | 1:1,000–1:5,000 |
| ELISA | 1:4,000–1:40,000 |
| Immunoprecipitation (IP) | 1:2,000–1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Capsular Reactive Protein (CRP) [Human Serum] |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Ion-exchange chromatography |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Store vial at 4°C prior to restoration.
- For extended storage, aliquot contents and freeze at -20°C or below.
- Avoid cycles of freezing and thawing.
- Centrifuge product if not completely clear after standing at room temperature.
- Product is stable for several weeks at 4°C as an undiluted liquid.
- Dilute only prior to immediate use.
Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Goat Serum as well as purified and partially purified Capsular Reactive Protein (CRP) [Human Serum].
Cross-reactivity against CRP from other tissues and species may occur but has not been specifically determined.
Target Information
CRP (C-reactive protein) is a major cyclic, pentameric acute-phase protein consisting of five identical, noncovalently bound, nonglycosylated subunits. Each subunit comprises 206 amino acids with a molecular weight of approximately 24 kDa.
CRP is synthesized by the liver, and its plasma concentration rises markedly during inflammatory processes. It acts as an initiator of the classical complement cascade, binds to nuclear components such as chromatin and histones, and plays a key role in innate immunity.
CRP levels can increase 100–1000 fold in response to injury, infection, or inflammation. It functions as an opsonin, activates monocytes/macrophages, and participates in host defense by recognizing pathogens and damaged cells. Elevated basal CRP levels are associated with increased risk of hypertension and cardiovascular disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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