Thermo Fisher Scientific mRELM beta Polyclonal Antibody
Mouse RELM beta 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot에 적합합니다. 합성 펩타이드(aa 32–46)를 면역원으로 사용하였으며, Protein A로 정제된 액상 형태입니다. -20°C 보관, 연구용 전용 시약입니다.
- 카탈로그번호
- 20805-100UG
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host/Isotype | Rabbit |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to aa 32–46 of mouse RELM beta protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.0 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Adipose tissue acts as a tightly regulated energy reserve in animals. Adipocytes secrete various physiologically important proteins, including lipoprotein lipase (LPL), leptin, Acrp30, perilipin, and resistin.
Resistin (also known as Adipocyte Secreted Factor, ADSF, or FIZZ3) is a cytokine secreted specifically by adipocytes. It has been implicated in type 2 diabetes, as elevated serum resistin levels in obese, diabetic mice have been associated with insulin antagonism.
Resistin gene expression requires C/EBP alpha and is modulated by coactivators CBP and p300, which acetylate histones at the resistin promoter. PPAR gamma and RXR ligands are known to downregulate resistin expression in adipocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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