Thermo Fisher Scientific CTLA4 Monoclonal Antibody (OTI9G4)

Applications

• Flow Cytometry (Flow): 1:400

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor primarily expressed on CD4+ T cells.
It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells) but with higher affinity.
Unlike CD28, which enhances T cell activation, CTLA4 inhibits T cell function. Intracellular CTLA4 is also found in regulatory T cells and may play a key role in their regulatory activity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.