Thermo Fisher Scientific ITGA3 Polyclonal Antibody, PE
마우스 ITGA3/CD49c 단백질을 인식하는 Thermo Fisher Scientific의 PE 결합 폴리클로날 항체입니다. Flow Cytometry에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 565/576 nm 형광 특성, 4°C 암소 보관, 연구용으로만 사용됩니다.
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Thermo Fisher Scientific ITGA3 Polyclonal Antibody, PE
Applications
- Flow Cytometry (Flow)
Tested Dilution: 10 µL per million cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host/Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Sf21-derived recombinant mouse Integrin alpha 3/CD49c (Phe33–Glu993) |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation/Emission Max | 565 / 576 nm |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Buffered saline solution with BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2607345 |
Product Specific Information
In direct ELISAs and Western blots, less than 1% cross-reactivity is observed with recombinant mouse Integrin alpha 2, 4, 5, E, M, V, and X.
Target Information
ITGA3 (Integrin, Alpha-3), also known as CD49C, VLA3, or GAPB3, is encoded by the ITGA3 gene. It is an integrin alpha subunit and a member of the cell surface adhesion molecule family. Located on chromosome 17q21.33, ITGA3 forms the alpha3beta1 integrin duplex that plays a role in neural migration and corticogenesis with the beta-1 subunit.
A functional link between DAB1 phosphorylation and ITGA3 signaling regulates neuronal detachment from radial glial fibers. Expression of human ITGA3 increases viral infectivity in CHO cells. ITGA3 contains 13 potential N-glycosylation sites, 2 cleavage sites, and 7 N-terminal repeating units typical of integrins. Recombinant ITGA3 is expressed as a 150 kD protein, matching the native form in Western blot analysis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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