Thermo Fisher Scientific HDAC7 Recombinant Rabbit Monoclonal Antibody (ARC0713)
HDAC7 단백질을 표적으로 하는 재조합 토끼 단클론 항체로, Western blot 및 ELISA에 최적화되어 있습니다. 인간, 마우스, 랫트 반응성이 있으며 HEK293 세포에서 발현되었습니다. 고순도 친화 크로마토그래피 정제 및 안정적 PBS/glycerol 저장용액 제공.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0713 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 24–198 of human HDAC7 (Q8WUI4) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.2 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849081 |
Product Specific Information
Immunogen sequence:
RPQRLHHHLF LAGLQQQRSV EPMRLSMDTP MPELQVGPQE QELRQLLHKD KSKRSAVASS VVKQKLAEVI LKKQQAALER TVHPNSPGIP YRTLEPLETE GATRSMLSSF LPPVPSLPSD PPEHFPLRKT VSEPNLKLRY KPKKSLERRK NPLLRKESAP PSLRRRPAET LGDSS
Target Information
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events.
Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA.
The protein encoded by this gene has sequence homology to members of the histone deacetylase family.
This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT.
Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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