Thermo Fisher Scientific TK1 Recombinant Rabbit Monoclonal Antibody (ARC0719)
인간 TK1 단백질을 인식하는 재조합 토끼 단클론 항체입니다. Western blot과 ELISA에 적합하며, 고순도 친화 크로마토그래피로 정제되었습니다. 안정한 액상 제형으로 -20°C 보관 시 장기 보존 가능합니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0719 |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 1–100 of human Thymidine Kinase 1 (P04183) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.42 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849084 |
Product Specific Information
Immunogen sequence:
MSCINLPTVL PGSPSKTRGQ IQVILGPMFS GKSTELMRRV RRFQIAQYKC LVIKYAKDTR YSSSFCTHDR NTMEALPACL LRDVAQEALG VAVIGIDEGQ
Target Information
Thymidine Kinase (TK1) is a highly conserved phosphotransferase present in most living cells. It catalyzes the phosphorylation reaction:
deoxythymidine + ATP → deoxythymidine 5′-phosphate + ADP.
This enzyme is essential for introducing deoxythymidine into DNA and is required for the action of many antiviral drugs such as azidothymidine (AZT). TK1 is also used in the selection of hybridoma cell lines for monoclonal antibody production and serves as a proliferation marker due to its expression during cell division.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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