Thermo Fisher Scientific HSPB8 Recombinant Rabbit Monoclonal Antibody (ARC0715)
HSPB8 단백질을 인식하는 Recombinant Rabbit Monoclonal Antibody. Western blot, ICC/IF, ELISA에 사용 가능. 인간, 마우스, 랫트 반응성. HEK293 세포 발현, Affinity Chromatography 정제. -20°C 보관, 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0715 |
| Immunogen | Synthetic peptide corresponding to amino acids 1–100 of human HSPB8/HSP22 (Q9UJY1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849082 |
Product Specific Information
Immunogen sequence:
MADGQMPFSC HYPSRLRRDP FRDSPLSSRL LDDGFGMDPF PDDLTASWPD WALPRLSSAW PGTLRSGMVP RGPTATARFG VPAEGRTPPP FPGEPWKVCV
Target Information
The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conserved alpha-crystallin domain at the C-terminal part of the molecule. Expression of this gene is induced by estrogen in estrogen receptor-positive breast cancer cells. This protein functions as a chaperone in association with Bag3, a stimulator of macroautophagy, and is involved in the regulation of cell proliferation, apoptosis, and carcinogenesis. Mutations in this gene have been associated with neuromuscular diseases, including Charcot-Marie-Tooth disease.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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