Thermo Fisher Scientific MKL1 Monoclonal Antibody (OTI1B5), TrueMAB
Human MKL1 단백질(aa 165-397)에 특이적인 Mouse IgG1 단클론 항체로 Western blot에 적합. Lyophilized 형태, PBS buffer에 trehalose 포함. 연구용으로만 사용 가능하며, 핵-세포골격 신호 전달 연구에 유용.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 165–397 of human MKL1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform additional desalting (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The MKL1 protein interacts with myocardin, a transcription factor regulating smooth muscle cell differentiation. It is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus.
This gene is involved in a translocation event that fuses MKL1 with the RNA-binding motif protein-15 gene, associated with acute megakaryocytic leukemia.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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(이미지 파일: CF805289_MKL1_Q969V6-1_House_mouse.svg, CF805289_MKL1_Q969V6-1_House_mouse_PDP.jpeg)
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