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Thermo Fisher Scientific Human RET [V804E], GST Tag Recombinant Protein
RET[V804E] 변이형 인간 재조합 단백질로, insect cell에서 발현된 GST-tag 형 kinase 단백질. Z'-LYTE™ assay에 검증되어 있으며, SelectScreen™ Kinase Profiling Service에서도 사용 가능. -80°C 보관, 고순도 정제된 액상 형태.
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- 3개 옵션
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Human RET [V804E], GST Tag Recombinant Protein
Applications
- Kinase Assay (KA)
Tested Dilution
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Expression System | Insect cells |
| Amino acid sequence | 858–1114 |
| Tag | GST-tag |
| Molecular weight | 80.5 kDa |
| Class | Recombinant |
| Type | Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Purified |
| Storage buffer | 50 mM HEPES (pH 7.5), 15 mM glutathione, 5 mM DTT, 20% glycerol, 100 mM NaCl |
| Contains | No preservative |
| Storage conditions | -80°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Dry ice |
Product Specific Information
- For maximum recovery, spin prior to use.
- Aliquots below 20 µL are not recommended.
- Never store kinase diluted.
- Guaranteed for 6 months when properly stored at -80°C.
- Expressed in insect cells (amino acids 858–1114).
- Available for use with Z'-LYTE™ assay.
- Offered in multiple pack sizes.
- Also available in SelectScreen™ Kinase Profiling Service.
Protein Form: Recombinant, Active, Cytoplasmic, Mutant
Gene accession number: NP_066124.1
Target Information
RET receptor tyrosine kinase (ret proto-oncogene) is a member of the cadherin superfamily involved in cell growth and differentiation signaling. RET can undergo oncogenic activation through cytogenetic rearrangements. Mutations are associated with:
- Multiple endocrine neoplasia type IIA and IIB
- Hirschsprung disease
- Medullary thyroid carcinoma
RET signaling regulates development of the nervous and lymphoid systems in the gut, playing a key role in intestinal organogenesis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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