Thermo Fisher Scientific MEK1 Polyclonal Antibody
MEK1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot에 적합합니다. MEK2 및 다른 MAP kinase와 교차반응하지 않으며, 항원 친화 크로마토그래피로 정제되었습니다. 세포 성장 및 신호전달 연구용으로 사용됩니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to human MEK1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11007638 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with MEK2 and other MAP kinase kinases.
Target Information
MAP2K1 (MEK1) kinase is a dual-specificity protein kinase functioning in mitogen-activated protein kinase (MAPK) cascades, controlling cell growth and differentiation. It is activated by a wide variety of growth factors, cytokines, membrane-dependent depolarization, and calcium influx. MEK1 activation occurs via phosphorylation of serine 218 and 222 residues by Raf1. It is involved in signaling during stress response, apoptosis, and proliferative induction by cytokines. Mutations in the gene can lead to cardiofaciocutaneous syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송 정보
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