Thermo Fisher Scientific Phospho-p130Cas (Tyr249) Polyclonal Antibody
인간, 마우스, 랫트에 반응하는 Rabbit IgG 폴리클로날 항체로 Tyr249 부위의 p130Cas 인산화 형태를 검출. Western blot에 적합하며 항원 친화 크로마토그래피로 정제됨. 액상 형태로 -20°C에 보관.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-p130Cas (Tyr249) Polyclonal Antibody
Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pTyr249 of human p130Cas |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES (pH 7.5), 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10979463 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
The p130Cas (Cas for Crk-associated substrate) is a common cellular target of phosphorylation signals via v-Crk and v-Src oncoproteins.
p130Cas has a unique structure containing a Src homology (SH)-3 domain followed by multiple YXXP motifs and a proline-rich region.
It is implicated in various biological processes such as:
- Cell adhesion and migration
- Growth factor stimulation
- Cytokine receptor engagement
- Bacterial infection
Physiological functions of p130Cas include cardiovascular development, actin filament assembly, and Src-induced cell transformation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 정보 없음)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.