Thermo Fisher Scientific CD79a Monoclonal Antibody (HM57), FITC
CD79a 단백질을 표적하는 HM57 클론의 FITC 결합 단일클론 항체로, B세포 발달 및 면역학 연구에 적합. Flow Cytometry에 최적화된 형광 검출용. 다양한 종에 반응하며 안정적인 액상 형태로 제공. 연구용 전용 제품.
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Thermo Fisher Scientific CD79a Monoclonal Antibody (HM57), FITC
Applications
- Flow Cytometry (Flow)
Tested Dilution: 4 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Chicken, Horse, Guinea pig, Human, Marsupial, Mouse, Pig, Rabbit, Rodent, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | HM57 |
| Immunogen | Synthetic peptide corresponding to amino acids 202–216 of human CD79a |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745499 |
Product Specific Information
The HM57 antibody interacts with the intracellular domain of CD79a (Ig alpha), a 40–45 kDa subunit of the B cell antigen-specific receptor (BCR) and its early developmental forms.
Recommended dilution: 100 µL of whole blood or 1×10⁶ cells in suspension.
Target Information
CD79a is a disulfide-linked heterodimer that includes B29 (CD79b) polypeptide. It acts as a B lymphocyte antigen receptor associated with Ig-alpha and Ig-beta, essential for expression and function of the B-cell antigen receptor.
CD79a appears at the pre-B cell stage and persists until the plasma cell stage as an intracellular component. It is found in most precursor B-cell acute leukemias, B cell lines, B cell lymphomas, and some myelomas, but not in myeloid or T cell lines.
Diseases associated with CD79a include Agammaglobulinemia 3 and Agammaglobulinemia, Non-Bruton type.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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