Thermo Fisher Scientific PFKP Recombinant Rabbit Monoclonal Antibody (5B7E3)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:4,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

5B7E3

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 336-540 of human PFKP (NP_002618.1). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PFKP,uniProtId:Q01813-1,ncbiNodeId:9606,antigenRange:336-540,antigenLength:784,antigenImageFileName:MA5-51364_PFKP_Q01813-1_Rabbit.svg,antigenImageFileNamePDP:MA5-51364_PFKP_Q01813-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_3094266

Product Specific Information

Immunogen sequence: ATPDTPACVV SLNGNHAVRL PLMECVQMTQ DVQKAMDERR FQDAVRLRGR SFAGNLNTYK RLAIKLPDDQ IPKTNCNVAV INVGAPAAGM NAAVRSAVRV GIADGHRMLA IYDGFDGFAK GQIKEIGWTD VGGWTGQGGS ILGTKRVLPG KYLEEIATQM RTHSINALLI IGGFEAYLGL LELSAAREKH EEFCVPMVMV PATVS

Target Information

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases including the cyclic nucleotide-regulated protein kinase (PKA & PKG) family, the diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family, the related to PKA and PKC (RAC/Akt) protein kinase family, the kinases that phosphorylate G protein-coupled receptors family (ARK), and the kinases that phosphorylate ribosomal protein S6 family (RSK).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.