Thermo Fisher Scientific EphA2/EphA3/EphA4 Polyclonal Antibody
EphA2, EphA3, EphA4 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot 및 Immunocytochemistry에 적합합니다. 비인산화 합성 펩타이드 면역원으로 제작되었으며, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic non-phosphopeptide derived from human EPHA2/3/4 around the phosphorylation site of Tyr588/596 (T-YP-V-D-P) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2555079 |
Target Information
The Eph subfamily represents the largest group of receptor protein tyrosine kinases identified to date. While the biological activities of these receptors have yet to be determined, there is increasing evidence that they are involved in central nervous system function and development.
The Eph subfamily receptors of human origin (and their murine/avian homologs) include:
EphA1 (Eph), EphA2 (Eck), EphA3 (Hek4), EphA4 (Hek8), EphA5 (Hek7), EphA6 (Hek12), EphA7 (Hek11/MDK1), EphA8 (Hek3), EphB1 (Hek6), EphB2 (Hek5), EphB3 (Cek10, Hek2), EphB4 (Htk), EphB5 (Hek9), and EphB6 (Mep).
Ligands for Eph receptors include ephrin-A4 (LERK-4), which binds EphA3 and EphB1. In addition, ephrin-A2 (Elf-1) has been described as the ligand for EphA4, ephrin-A3 (Ehk1-L) as the ligand for EphA5, and ephrin-B2 (Htk-L) as the ligand for EphB4 (Htk).
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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