
Thermo Fisher Scientific ICOS Monoclonal Antibody (OTI5B7)
ICOS 단백질을 표적으로 하는 마우스 모노클로날 항체(OTI5B7)로, Flow Cytometry에 적합합니다. 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용 가능합니다. 인간 시료 반응성이 있으며, 연구용으로만 사용됩니다.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 1:100–1:400
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5B7 |
| Immunogen | Full length human recombinant protein of human ICOS (NP_036224) produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
ICOS (CD278) encodes a protein belonging to the CD28 and CTLA-4 cell-surface receptor family.
It functions as a homodimer and plays a crucial role in:
- Cell-cell signaling
- Immune response regulation
- Cell proliferation
ICOS has been associated with disorders such as Immunodeficiency, Common Variable, 1 and Common Variable Immunodeficiency.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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