Thermo Fisher Scientific CD70 Monoclonal Antibody (OTI7B2)
인간 CD70 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Flow Cytometry에 1:100 희석으로 사용 가능. 무보존제, 동결건조 형태이며 PBS + 8% trehalose 버퍼에 저장. T세포 및 B세포 활성화 연구용으로 적합.
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Applications
- Flow Cytometry (Flow): Tested dilution 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7B2 |
| Immunogen | Full length human recombinant protein of human CD70 (NP_001243) produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional round of desalting (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The protein encoded by the CD70 gene is a cytokine belonging to the tumor necrosis factor (TNF) ligand family.
It acts as a ligand for TNFRSF27/CD27 and is expressed on activated T and B lymphocytes, but not on resting cells.
Functions include:
- Induction of proliferation in costimulated T cells
- Enhancement of cytolytic T cell generation
- Contribution to T cell activation
- Regulation of B-cell activation, NK cell cytotoxicity, and immunoglobulin synthesis
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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