Thermo Fisher Scientific ICOS Monoclonal Antibody (OTI5G8)
ICOS 단백질을 인식하는 마우스 단클론 항체로, Flow Cytometry에 적합합니다. HEK293T 세포에서 발현된 full-length 인간 ICOS 단백질로 면역화되었습니다. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용 가능합니다. 연구용 전용 제품입니다.
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Applications
- Flow Cytometry (Flow): 1:100–1:400 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5G8 |
| Immunogen | Full-length human recombinant protein of human ICOS (NP_036224) produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
ICOS (CD278) encodes a protein that belongs to the CD28 and CTLA-4 cell-surface receptor family. It functions as a homodimer and plays a crucial role in:
- Cell-cell signaling
- Immune response regulation
- Cell proliferation control
Mutations or dysregulation of ICOS are associated with disorders such as Common Variable Immunodeficiency (CVID).
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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